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We're sending this greeting Full of holiday cheer To you, very special people: Merry Christmas and a Happy New Year! Wishing you all health, joy and prosperity, Life Chemicals Team Featured Products Read More Cysteine Protease Screening Libraries updated Cysteine proteases are promising drug targets for various diseases: cancer, cardiovascular and inflammatory diseases, thrombosis, AIDS, pancreatitis, and neurological disorders. To facilitate small-molecule HTS in cysteine protease-related drug discovery projects, we designed two dedicated Screening Sets of drug-like molecules that are potential cysteine protease modulators. Read More Antibacterial Screening Compound Library updated Explore over 18,000 drug-like molecules with potential bacterial inhibitory activity against different gram-positive and gram-negative bacteria species, as well as bacteria-related protein targets. The focused screening set, selected with 2D fingerprint similarity, open for cherry-picking and available in the pre-plated format. Additional docking-based compound set against the most relevant pneumonia-causing bacterial drug targets was selected by virtual molecular screening. Read More Pre-plated Screening Compound Sets updated To make your drug discovery research even more rewarding, we carefully design and update our constantly-growing collection of readily-available pre-plated screening sets. Based on our best-selling products, these assay-ready Pre-plated Screening Pools have already proven to be an auspicious and efficient starting point for HTS, HCS and FBDD campaigns in drug discovery. Read More Cyclin-dependent Kinase Focused Libraries new The cell division cycle is controlled by cyclin-dependent kinases (CDKs). The search for novel CDK inhibitors is a hot topic in current anticancer drug discovery research. We present over 1,700 small-molecule screening compounds targeting CDK7 and CDK2 that were selected via receptor-based virtual screening. Read More Fsp³-enriched Screening Compound Library updated 62,000 sp3-rich non-flat screening compounds from the Life Chemicals proprietary HTS Compound Collection. These novel drug-like molecules possess an increased Fsp3 fraction ≥ 0.47 (mean value 0.57), as well as high chemical and structural diversity. Many structures contain spiro, bridged and fused rings and stereogenic centers to cover more advantageous chemical space. Read More Fragment Diversity Subsets for FBDD updated Our profound expertise in medicinal chemistry allowed us to prepare compact screening sets as a perfect starting point for FBDD campaigns. They contain 960 or 1,600 of our best fragment-like molecules with maximal structure dissimilarity to cover the broadest chemical space. Providing the most suitable solutions to different research tasks, available are specific subsets which include fluorinated and brominated compounds, Fsp³-enriched molecules, and potential covalent binders. Read More Ion Channel Screening Libraries updated Although ion channels are the key players of communication in the nervous system, they are underexploited molecular targets in drug development. Here and now, the wonderful world of ion channels can expertly be targeted with our screening compounds. To boost the discovery of novel ion channel ligands, we offer structurally-diverse screening compounds that are potential small-molecule ion channel modulators, selected by both ligand-based and receptor-based approaches. Read More RNA Focused and Targeted Libraries updated Belonging to the three major biological macromolecules essential for all known forms of life, RNA is involved in the progression of various diseases, including infectious (HIV, hepatitis C), metabolic (diabetes, cancer), and triplet repeat (myotonic dystrophy, Huntington’s disease) disorders. Life Chemicals has always devoted itself to tackling most essential R & D problems and in doing so, we offer 3,300 drug-like compounds with predicted RNA-binding activity as an excellent starting point for post-transcriptional gene regulation, antibacterial, and antiviral drug discovery. Subscribe to our newsletter: Latest News Read More December 06, 2022 In Vitro ADMET, Physicochemical and Biochemical Tests for Early-stage Drug Discovery High-resolution mass spectrometry services, physicochemical compound profiling as well as enzyme assays are available on request to facilitate your research projects. Read More November 30, 2022 World AIDS Day 2022 Life Chemicals supports World AIDS Day 2022 by offering its proprietary set of Screening Compound Libraries, including pipeline compounds for drug discovery projects. Read More November 11, 2022 World Diabetes Day 2022 Dedicated to World Diabetes Day 2022, Life Chemicals is offering its proprietary collection of Screening Compound Libraries to support diabetes-related drug development efforts. News Archive Life Chemicals to participate in: 3rd MMCS - Molecules Medicinal Chemistry Symposium July 27-29, 2022 Rome, Italy EFMC-ISMC 2022 September 4-8, 2022 Nice, France 2022 NESACS Annual Advances in Chemical Sciences Symposium October 7, 2022 Waltham, MA 02451, United States All Events Copyright © 2022 Life Chemicals All rights reserved. Privacy & Terms Novel small molecules, custom chemistry, early drug discovery services Contact Life Chemicals Worldwide orders@lifechemicals.com +1 800 591 9710 This site uses cookies. Some of these cookies are essential, while others help us improve your experience by providing insights into how the site is being used. By using our website, you accept our conditions of use of cookies to track data and create content (including advertising) based on your interest. Accept We are proud of Ukraine’s resilience! Dear Customer, Life Chemicals has fully resumed its production and services at its Kyiv site, supporting its customers’ HTS and building blocks programs and contributing to the restoration of the country’s economy! Always new and best chemistry – yours to explore! You can place orders and inquiries for the whole stock of our Screening Compounds and Building Blocks . Contact us at orders@lifechemicals.com for more information and quotations. The Life Chemicals Team is confident of the Company’s strong potential to quickly and successfully restart and grow, keeping pace with the highest market demands! STAND WITH UKRAINE: CLICK TO DONATE! For your convenience, we have also prepared a list of our selected products that are readily available for swift delivery worldwide directly from our USA- and Germany-based facilities: Pre-plated Diversity Sets , Pre-plated Focused Libraries , Pre-plated Fragment Screening Sets , Building Blocks (USA & EU Stock) . Please note that Ukranian courier services are not completely operational due to Russia’s invasion of Ukraine, and the delivery time for the main stock may take longer than usual. Thank you for your understanding and support! Yours sincerely, Life Chemicals team Close