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Main publication: 1 Martynov A.V., Kislichenko V.S. Synthesis and properties of clathrate complexes between acylated immunoglobulins and low molecular weight substances // Pharm . J.-2004.- Vol. 2.- P.48-52 2 Martynov A.V. , Smilanskaya M.V., Peremot S.D. Studying of viral adhesion inhibitor p-carbetoxy –N-phenylaconitimid on in vovo model // Drugs.-1999.- N 3-4.- P.79-81 (Ukr) 3 Martnov A.V., Smilanskaya M.V., Kuchma I.Yu., Peremot S.D. Antiviral activity of aconitic acid imides – new class of substances // News in pharmacy .- 1998.-Vol.2, N.18.-P.97-99 (Ukr) 4 Martynov A.V., Kislichenko V.S., Smilanskaya M.V., Peremot S.D., Sapoznicova N.F. Studying of Ribes nigrum some extracts in anticancer effect // Clinical Pharmacy.- 1998.-Vol.2, N 3.-P.89-91 5 Martynov A.V., Smilanskaya M.V., Peremot S.D. Studying of imides 2- and 3- carboxylic acid imides and albumines derivatives in antiviral effects // Drugs.- 2000.-N 6.-P.51-54 (Ukr) 6 Martynov A.V., Smilanskaya M.V., Peremot S.D. Antiviral effect of polyanionic albumin in C-2 therapeutic system // Drugs.- 2002.-N 1-2.-P.39-42 (Ukr) 7 Martynov A.V., Smilansaya M.V., Popova N.V., Kislichenko V.S., Kozuch I.O., Volkovich O.O., Tkachenko O.Yu. Studying vegetable proteoglycans and polysaccharides in therapeutic system C-2 on antiviral properties // Pharm. J.-2001.-N 4.-P.74-77 (Ukr) 8 Martynov A.V., Chernych V.P. High-molecular weigh drugs – biotechnology products- chemical modification as instrument of precise influence on its pharmacology properties // Clin. Pharmacy.- 2002.- Vol.6, N.3.-P.3-8 (Ukr) 9 Kovalev V.N., Martynov A.V., Krasnicova T.O., Stepanova S.I. Vegetable lectins as biological active substances for drugs development // Phys. Act.Subst.-2001.- N 1 (31).- P.74-78 (Ukr) 10 Chernych V.P., Martynov A.V. Synthesis and biological activity of acylated tannins // Phys. Act.Subst.-2001.- N 2 (32).- P.16-19 (Ukr) 1 1 Dikiy I.L., Martynov A.V. Differential – rethrotranspositional theory of cancerogenesis// News in Pharmacy.- 1997.- N 1(15).-P.88-93. (Ukr) 1 2 Schemchuk L.A., Chernych V.P., Martynov A.V. Synthesis of trans-aconitic acid imides // J. Org.Chem (Rus).- 1997.-Vol.33, N 3.-P.1257-1259 1 3 Martynov A.V., Smilanskaya M.V., Kozuch I.A., Volkovich O.O., Popova N.V., Kislichenko V.S. Anticancer effects of vegetable glicoproteins, that affinity to G-class immunoglobulins // Pharm. J.-2000.-N 5.-P.78-80 (Ukr) 14 Martynov A . V ., Babkin M . V ., Prochoriatova E . V ., Smilanskaya M . V ., Peremot S . D ., Gadzevich D . V ., Stecenko O . V ., Volkova V . V ., Rudenko M . V . 1,5- pipiredil -3,7- bis ( dietanolamino ) – pirimidilisovalerianat for viral infection diagnostics // Ukrainian Patent # 37622 A 1 5 Martyniv A . V ., Smilanskaya M . V ., Parchomenko A . A ., Pamchenko L . A ., Kuchma I . Yu ., Chernych V . P ., Schemchuk L . A . p - carbetoxyphenylaconitimid with antiviral properties toward vesicular stomatitis virus and herpes simplex virus // Ukrainian patent # 22189 A. 16 Smelyanskaya M . V ., Prochoriatova E . V ., Babkin V . F ., Panchenko L . A ., Volyansky A . Yu ., Chodak L . A ., Martynov A . V ., Pochil S . I ., Kuchma I . Yu ., Lisnyak Yu . V . Method of viruses detection // Ukrainian patents # 23678 A . 17 Khaled A.Z., Zuravlev N.S., Martynov A.V. Studying of catechines and leucoantocyanidines of dock families for photodynamic anticancer activity // Pharmacom.-2002.-N 2-P.105-107 1 8 Martynov A . V ., Kislichenko V . S ., Tkachenko O . Yu ., Vinnik O.V. Technological aspects of injectable Ribes Nigrum anticancer proteoglicans // News in pharmacy.- 2002.-N 1(29).- P.33-35 1 9 Martynov A.V., Chernych V.P. Synthesis and biological properties of immunoglobulins, acylated by succinia cnhydrides // News in pharmacy.- 2002.- N 3 (31).- P.13-16 20 Litvinenko V . I ., Martynov A . V ., Popova N . V ., Kozuch I.A. Some technological and biopharmaceutical features of Bergenia lectines extraction // Pharmacom.- 2002.-N 3.- P.18-21 2 1 Martynov A.V., Chernych V.P. Drug-design and synthesis of antiviral substances – nuclear import signals inhibitors – from succinylated peptides group // News in pharmacy.- 2003.- N 1 (33).- P.3-6. 2 2 Martynov A.V. Synthesis and properties of succinylated polynucleotides // News in Pharm.- 2003.-N 2(34).- P.20-23 2 3 Martynov A.V., Chernych V.P. Synthesis and biological properties of vegetable proteins, succinic anhydride acylated // Drugs.-2003.-N 1-2, P.73-76 2 4 Martynov A.V., Chernych V.P. Synthesis and antiproliferative properties of succinylated and aconitylated derivatives of recombinant a -2b-interferons // Exp . Oncology . - 2003.- Vol . 25, N 4. – P . 52-54 25 Martynov A.V. Studying of structure – activity dependence in recombinant a -2- b - interferon succinylated derivatives // News in Pharm.-2003.-N 4 (36).-P.18-21 2 6 Martynov A.V., Chernyh V.P. Features of antiviral polyanionic biopolymers exuberant negative charge definitions in its structure analysis // News in Pharm.- 2004.- N 1(37).-P.3-6 2 7 Poteyko P . I ., Martynov A . V ., Smelyanskaya M . V ., Peremot S . D ., Kireev I . V . Experience of tuberculosis patients treatment with used anticytomegalovirus polyclonal immunoglobulins // Med . today and tomorrow .- 2003.-N 4.-P.88-91 2 8 Martynov A . V ., Smelyanskaya M . V ., Kuchma I . Yu ., Chernych V . P ., Parchomenco A . A . β-D- glucosammonium salt of α- bromisovaleric acid with antiviral activity for vesicular stomatitis virus, herpes simplex virus and coronavirus // Ukrainian Patent N 23352 А. 2 9 Smelyanskaya M.V., Martynov A.V. Features of used of new drug with antiviral activity – Alfavir for HCMV treatment // Vesn. Probl.of boil.and med. -1997.-Vol.14.- P.83-88 30 Peremot S.D., Smelyanskaya M.V., Martynov A.V. Toxoplasmosis laboratory diagnostics and criteria of it examination // Vesn. Probl.of boil.and med. -1998.-Vol.23.- P.65-68 31 Diky I.L., Martynov A.V. About question of target cancer therapy. Used of polyclonal immunoglobulins for chemeric affinotoxins receptions // Vesn. Probl.of boil.and med. -19998.-Vol.17.- P.101-107 3 2 Smelyanskaya M . V ., Sanina E . V ., Peremot S . D ., Kuchma I . Yu ., Martynov A.V. Clinical and laboratory aspects of mother – child infection at the present stage // Medical news .- 1998.-N 2.-P.10-12 3 3 Prochoriatova E.V., Bila N.V., Volkova V.V., Martynov A.V. Studying of infections laryngotracheitis virus and New-Castle Virus in ovo // Veterenary medicine .- 2000.-Vol.1, N 78.-P.251-255 3 4 Martynov A . V ., Shmatko Yu . V ., Smelyanskaya M.V., Peremot S.D., Vinnik Yu.M. Detection of herpes virus type 1 antigen in lymphocytes and tumor tissue of patients with cancer of uterus // Exp . Oncology . - 2002.- Vol . 24, N 2. – P .120-122 3 5 Martynov A.V., Volyanskaya N.P. Studying of alfavir medical effects in rabbits ophtalmogerpes model // Vesn. Vin. Derg.Med.Univ.-2002.- N 2.-P.311-313 3 6 Marashina T.A., Psechenko N.V., Osolodchenko T.P., Martynov A.V., Paranich A.V., Savchenko S.P. Pathogenic value of antioxidant homeostasis in mice with escherichiosis // Vesn. Probl.of boil.and med. -2002.-Vol.5.- P.17-21 3 7 Application for Ukrainian patent 98062886 03.06.1998 MKI 6 А 61 К 31/00, 6 С 12 N 7/00 / Method of ointment reception for treatment of diseases, caused by intracells infections // Martynov A.V., Smilanskaya M.V., Peremot S.D., Kuchma I.Yu., Volyansky A.Yu., Mizger T.G., Dgurovich R., Dobroscok O.I. 3 8 Application for Ukrainian patent 96124561 from 05.12.1996 MKI 6 А 61 К 31/16, С 07Н 5/06 // Aconitanilic acid glucosammonium salts with anticancer activity// Martynov A.V., Chernych V.P., Smilanskaya M.V., Volyansky A.Yu., Schemcuk L.A. 3 9 Application for Ukrainian patent 97105000 from 13.10.1997 MKI 6 А 61 К 35/14 // Methods of adoptive immunotherapy of cancer // Martynov A.V., Volyansky Yu.L., Dobroscok O.I., Kuchma I.Yu., Malcev V.I., Moskalenko V.F., Dgurovich R., Tarasov O.A. 40 Kuchma I . Yu ., Volyansky A . Yu ., Moskalenko V . F ., Tkachuk T . B ., Dobroskok A . I ., Martynov A . V ., Smelyanskaya M . V ., Peremot S . D . Using of cis - aconitic acid phenylimides in liposomal form for herpes treatment // J . Micr . Epid . Immunobiol .-2000.- N 5.- P .58-61 41 Babich E . M ., Kolokolova E . E ., Volyansky Yu . L ., Krasnopolsky Yu . M ., Martynov A . V ., Verezub L . G ., Belozersky V . I ., Sklyar N . I ., Volyanskaya N . P . Studying of Bordetella Pertussis antigens liposomal form ajuvanticity with oral used // Exp . And clin.med.-2002.-N 3.-P.87-90 4 2 Martynov A . V . Analysis of the low effectiveness causes of modern treatment methods of cancer mal - formations // Ann . Mech . Inst .-2002.- N 2-3.- P .57-60 43 Method of tuberculosis patients treatment by anticytomegalovirus polyclonal immunoglobulins / Poteyko P . I ., Martynov A . V ., Smilyanskaya M . V ., Chernyavsky V . I ., Peremot S . D ., Kuchma I . Yu ., Bozko M . G ., Nomerovchenko V . M . // MKI 7 А61К39/00, А61К39/12, А61К39/390 Ukrainian patent N 63791 А from 63791 А, publ . . 15.01.2004., bull . N 1. 4 4 Litsmanova N.V., Martynov A.V., Paranitch A.V., Svich V.A., Marishina T.A. Stability ob lipide bilayer and it laser light modification // ХІV Int. Sc.-pract. Confer “Application of lasers in biology and medicine” 2000, may 16-19, Kharkov., P.8-9 4 5 Martynov A.V., Smelyanskaya M.V. Studying of autoadopting immunoliposomal system for selective targeting of drugs to cancer cells // Resp. Sc. Conf. “ Scientific directions in drug-design in Ukrainian pharmacy 2000, sept. 26-28 Kharkov.-P.61-62 4 6 Litsmsnova N., Paranich A., Martynov A., Marishina T. Stability of lipid bilayer in model systems and methods of its modification/ Eur. Bioph.J.-2000.- Vol.29, N 4-5.-P.293-294. 4 7 Martynov A.V., Volyanskaya N.P. Medical effect of alfavir for rabbit ophtalmoherpes treatment // Int. Sc.-Pract. Conf. “Actual questions of strategy and practical in used of antiseptics and antibiotics” 2002, sept. 11-12, Vinnitca. 4 8 Martynov A.V., Kuchma I.Yu. Transposones as a factors of viruses, microorganisms and cancer cells pathogenicity // Int. Sc.Conf “Strategy and tactics in struggle wits infectious diseases” Kharkov 2001. P.12. 49 Martynov A.V., Peremot S.D., Smelyanskaya M.V. Herpesviruses as a fector of immune reaction disbalance in cancer patients // Int. Sc.Conf. “Strategy and tactics of infectious diseases struggle” Kharkov, Oct. 23-24. 2001.-P.15-16 50 Popova N . V ., Litvinenko V . I ., Martynov A . V ., Volkovich O . A . Helichrisum arenarium – perspective plant // Achievements of a modern pharmaceutics and prospect of its development in a new millennium. V national congress of Ukrainian pharmacist.-Kharkov, 1999.-P.322-333 5 1 Martynov A.V. Proteines and multiple protein ensemble acylation as a method for its biological activity increased // VII Int. Med.Congr. Stud. And young Sc. May 21-23, 2003.- P.256 5 2 Martynov A.V., Smilyanskaya M.V., Peremot S.D. Development of b-importin nuclear import signals inhibitors – succinylated peptides – for clear of cancer cells and immunocytes from persistence herpesviruses // Oncology -2003.- Vol.5 , N 2.- P.174-175 53 Smelyanskaya M.V., Peremot S.D., Kireev I.V., Samura B.B. Using of specific “Biopharma” immunoglobulin for antiviral immunorehabilitation of patients with herpesviral persistence // Ukr. Sc.-Pract. Conf. “Drugs for human”.18/12/2003.-Kharkov. P. 143-144 5 4 Smelyanskaya M.V., Martynov A.V., Peremot S.D. Substantiation of application of immunorehabilitation for patients with herpesviral persistence // Rus. Congress of doctors-infectionists.- 29-31.10.2003.- Sankt-Petersburg (Russia).- P.361 5 5 Fundamental research of antiviral and anticancer drugs with targeting properties. // Report of Sc.-Res. Work.// IMI.- CFFN 42498, Gov. reg. N 0198 U 002478 .- Kharkov., 2001.- 94 P. 5 6 Development of anatoxins and somatic antigens immunifacient entheral forms for nonparentheral vaccines reception for diphtheria, meningococcus and pertussis prophylaxis // Report of Sc.-Res. Work.// IMI.- CF 4.32.99 , Gov. reg. N 0199 U 003173 .- Kharkov.-2001.-142 P. 5 7 Development of immunorehabilitation methods for cancer patients with herpesviral persistence ./ / IMI.- АМ S 41/2001; Gov. reg. N 0101 U 001117.- Kharkov ., 2002.-112 p . 58 Martynov A.V., Timchenko E.N., Pochil S.I. Chemically modified specific immunoglobulins for laboratory diagnostics of legioneliosis // Microb.Z.-2005.-67(3).- P. 61-71 (Ukr) 59 Мartynov А.V., Smelyanskaya M.V. Antiproliferative properties of chemically modified a -2b-recombinant interferon // J. of Interf. & Cytokine res.- 2005.-Vol. 25, N 7.- P. 414-417 (Engl) 60 Martynov A.V., Smelyanskaya M.V. , Peremot S.D., Sorochan P.P., Nikiforova N.A. Correlation between herpesviral persistence in immunocytes and condition of immune system in cancer patients // J. of AMSU. -2004.-10(2).- P.385-391 (Ukr) 61 Pshechenko, N., Paranich, A., Martynov, A., Svitch, V., Marishina, T Liposomes for the treatment of inoculation colibacteriosis of a mice // Euromedlab (Int.Congress).- 2001.- PO-B024 ( http://www.congress.cls.cz/euromedlab2001/ [http://www.congress.cls.cz/euromedlab2001/] ) (Engl) 62 Pshechenko, N., Paranich, A., Martynov, A., Svitch, V., Marishina, T. The using of perspective medicinal form – liposomes for the treatment of inoculation colibacteriosis of a mice // Euromedlab. (Int.Congress) - 2001.- PO-W037 ( http://www.congress.cls.cz/euromedlab2001 ) (Engl) 63 Lisnyak Yu.V., Gubskaya A.V., Martynov A.V. b-Cyclodextrin inclusion complexes with methylxanthines. Molecular mechanics accounting for the solvent. // MACC-1, Kharkiv, 30 June- 1 July 2005. –P. 49 (Engl) 64 Martynov A.V. New approach to synthesis of trans-aconitic acid imides // RJOC.-2005.-41(5).- P. 731-734 65 Martynov A.V., Smelyanskaya M.V. , Peremot S.D., Sorochan P.P., Nikiforova N.A. Influence of herpesviral persistence in immunocytes on immune system of cancer patients // Modern infections.- 2004.-1.-P.25-30